Metronidazole is an antibiotic used to treat a wide range of bacterial and parasitic infections in various parts of the body[1].
- Abdominal infections, such as peritonitis
- Skin and soft tissue infections
- Infections of the female reproductive system (e.g., bacterial vaginosis, endometritis, pelvic inflammatory disease)
- Bloodstream (septicemia) and bone or joint infections
- Infections of the brain and spinal cord membranes (meningitis)
- Lung infections, such as pneumonia or empyema
- Infections of the heart and heart valves (endocarditis)
- Certain sexually transmitted infections (notably trichomoniasis)
- Intestinal infections caused by parasites (such as amebiasis and giardiasis)
- Prevention of infections after certain surgeries, especially involving the digestive tract
- Oral and dental infections, including dental abscesses and gum infections
- Rosacea and other inflammatory skin conditions (topical forms)
Metronidazole is also sometimes used off-label for conditions like Crohn’s disease, Helicobacter pylori infection, prevention of preterm birth, and periodontal disease[3].
This medication is available in several forms, including tablets, capsules, oral suspension, topical gel or cream, and by injection (typically used in a hospital setting)[1][7].
It works by damaging the DNA of susceptible organisms, leading to their death[1][6]. It is not effective against viral infections, such as the common cold or flu[5][8].
References
- [1] Metronidazole (Flagyl, Likmez) – Uses, Side Effects, and More – WebMD
- [3] Metronidazole: Uses, Interactions, Mechanism of Action – DrugBank
- [5] Metronidazole: MedlinePlus Drug Information
- [6] Metronidazole: Uses, Dosage, Side Effects, Warnings – Drugs.com
- [7] About metronidazole – NHS
- [8] Metronidazole (oral route) – Mayo Clinic