Diaglucide MR 60mg (with the active ingredient gliclazide) is an oral antidiabetic medication used to treat type 2 diabetes mellitus in adults when lifestyle changes—such as diet, exercise, and weight loss—do not sufficiently control blood sugar levels[1][2][3][4]. It belongs to the sulfonylurea class of drugs and works by stimulating the pancreas to release more insulin, which helps to lower blood glucose[1][4][7].
This medication is usually used as part of a comprehensive diabetes management plan, which may also include other oral antidiabetic drugs or insulin if necessary[3]. Its modified release (MR) formulation allows for once-daily dosing, which may aid adherence[2][7].
Key uses of Diaglucide MR 60mg include:
- Lowering blood sugar levels in adults with type 2 diabetes whose blood sugar is not adequately controlled by diet, exercise, and weight loss alone[1][2][3].
- Treatment can be initiated when metformin or other first-line therapies are not tolerated or are insufficient to achieve glycemic targets[4][7].
- It is effective in reducing fasting and postprandial blood glucose as well as HbA1c (a marker of long-term glucose control)[5][7].
Diaglucide MR 60mg is not suitable for:
- People with type 1 diabetes
- Individuals with diabetic ketoacidosis, pre-coma, or diabetic coma
- Those with severe liver or kidney disease
- Individuals allergic to gliclazide, other sulfonylureas, or sulphonamides
- Pregnant or breastfeeding women
- Anyone taking specific interacting drugs (e.g., miconazole)[1][2]
As with other sulfonylureas, Diaglucide MR 60mg may cause side effects, the most significant being hypoglycemia (low blood sugar), especially in the elderly or if meals are skipped[3][4][7].
References
- [1] Indications of Diamicron MR 60mg – Vinmec
- [2] GLICLAZIDE 60 MG MR TABLETS – Drugs.com
- [3] Ardix Gliclazide 60 mg MR – NPS MedicineWise
- [4] Gliclazide – Wikipedia
- [5] Effectiveness of gliclazide MR 60 mg in the management of type 2 …
- [7] Gliclazide: Uses, Interactions, Mechanism of Action | DrugBank Online