Adco Napamol is a combination medicine containing naproxen and paracetamol (acetaminophen), primarily used for pain relief and the reduction of fever. This combination is effective because naproxen functions as a non-steroidal anti-inflammatory drug (NSAID), reducing inflammation and swelling, while paracetamol is an analgesic and antipyretic, relieving pain and fever without anti-inflammatory properties[2].
The combined use of naproxen and paracetamol is indicated for a variety of conditions involving mild to moderate pain, such as:
- Osteoarthritis, rheumatoid arthritis, and other musculoskeletal disorders
- Back pain and joint pain
- Menstrual cramps
- Headache and migraine
- Postoperative or post-injury pain[3][6]
Clinical studies indicate that combining naproxen with paracetamol can enhance pain relief compared to naproxen alone, especially in conditions like rheumatoid arthritis, without substantially increasing gastrointestinal side effects[1].
The combination is generally considered safe for short-term use, though patients should adhere to prescribed dosages to avoid risks such as gastrointestinal irritation from naproxen or liver toxicity from excessive paracetamol[4][6]. Typical adult dosing with combination products follows similar guidelines to separate-form dosing: the maximum daily dose is usually up to 660 mg naproxen and 4,000 mg paracetamol[6].
Combination products are available by prescription and over-the-counter in some regions[5][6]. The NHS and other authorities advise that it is safe for most people to use these medications together for a limited duration. However, if extended use is required, or if patients have additional health risks or take other medications, consultation with a healthcare provider is recommended[4].
References
- [1] Additive effect of combined naproxen and paracetamol in rheumatoid arthritis – PubMed
- [2] Can I take Naproxen and Paracetamol together? – e-Surgery
- [3] Naproxen + Paracetamol: View Uses, Side Effects and Medicines – 1mg
- [4] Taking naproxen with other medicines and herbal supplements – NHS
- [5] Bioequivalence of naproxen sodium/paracetamol combinations – PubMed
- [6] What is Proxalin-Plus used for? – Drugs.com
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