Iruxol ointment is primarily used for the enzymatic debridement of necrotizing or dead tissue in wounds, especially in cases such as leg ulcers, decubitus (pressure) ulcers, diabetic gangrene, frostbite, poorly healing wounds after surgery or radiotherapy, burns, and before skin grafting[1]. The ointment contains proteolytic enzymes (like clostridiopeptidase A/collagenase) that break down and remove dead tissue, promoting wound cleansing and speeding up the healing process[4].
Specifically, the main uses of Iruxol ointment include:
- Debridement (cleaning and removal) of necrotic (dead) tissue in chronic wounds such as leg ulcers, diabetic ulcers, pressure sores, and wounds with gangrene[1][4].
- Treatment of skin ulcers of various origins and reduction of superficial bacteria, especially in small-sized ulcers[2][6].
- Facilitation of healing in poorly healing wounds, chronic lesions (such as those with impaired blood supply or metabolic disturbances), and burns[1][4].
- Preoperative preparation of wounds before procedures like skin grafting, by ensuring a cleaner wound bed[1].
- Potential to accelerate healing in soft tissue defects, possibly reducing the need for plastic surgery in some cases[5].
Iruxol ointment is generally well tolerated, but it should not be used in patients allergic to its ingredients. It should also be avoided on extensive skin areas, as systemic absorption (especially of certain components like neomycin in some formulations) may cause adverse effects, particularly in those with kidney disease or concurrent aminoglycoside antibiotic therapy[2][6]. Always follow specific medical advice on dosage and use.
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