Medazine contains cyclizine hydrochloride, an antihistamine used primarily to prevent and treat nausea, vomiting, and dizziness associated with motion sickness and certain inner ear disorders, such as Ménière’s disease[2][4][8].
Its principal uses include:
- Prevention and treatment of nausea and vomiting caused by motion sickness, postoperative recovery (after anesthesia), or as a result of opioid use[1][5][7].
- Relief of vertigo and dizziness caused by inner ear problems like Ménière’s disease and labyrinthine disorders[2][5][8].
- May be used in specific situations for nausea related to radiotherapy, particularly when other treatments are unsuitable[5].
It is generally administered orally, but can also be given rectally or by injection in some medical contexts[1][8]. Cyclizine, the active component, works by blocking histamine receptors in the brain that are responsible for triggering feelings of nausea and dizziness[6][7]. Medazine should be taken about 30 minutes before travel when used for motion sickness[8].
Contraindications: Medazine should not be used:
- In people allergic to cyclizine or its ingredients
- In those with acute asthma, narrow-angle glaucoma, prostatic enlargement, difficulty urinating, or certain lung diseases
- During pregnancy and breastfeeding, unless advised by a doctor, as safety is not established[2][8]
References
- [1] Cyclizine – Wikipedia
- [2] medazine s – PI and PIL Repository
- [4] MEDAZINE 50MG TABLETS 20 – Broadway Pharmacy
- [5] Medazine : Uses, Side Effects, Interactions, Dosage / Pillintrip
- [6] Cyclizine: an anti-sickness medicine
- [7] Cyclizine: Uses, Interactions, Mechanism of Action | DrugBank Online
- [8] MEDAZINE SYRUP – PI and PIL Repository
Leave a Reply