Nexium (esomeprazole) tablets are primarily used to treat conditions related to excessive stomach acid, including gastroesophageal reflux disease (GERD), duodenal and gastric ulcers, and erosive esophagitis[1][3][5]. They may also be indicated for Zollinger-Ellison syndrome and for the prevention of ulcers due to the use of nonsteroidal anti-inflammatory drugs (NSAIDs)[1].
The tablets work by reducing stomach acid production, helping heal acid-related damage, alleviate heartburn, and prevent ulcer formation[1][3][6].
- Used to treat heartburn and acid reflux disorders such as GERD[1][6].
- Helps heal and prevent ulcers in the stomach and duodenum[1][5].
- Prevents damage to the esophagus caused by acid, known as erosive esophagitis[1].
- Reduces the risk of ulcers for people taking NSAIDs[1].
- Treats Zollinger-Ellison syndrome, a rare disorder causing excessive acid production[1].
Dosage and administration: Nexium is usually taken once daily, 1 hour before eating, but can be prescribed twice daily for some conditions. Tablets should be swallowed whole and not crushed or chewed[1][3].
Common side effects include headache, nausea, abdominal pain, diarrhea, constipation, flatulence, dry mouth, and sleepiness[1][2][3][4][5].
Rare but serious side effects may include kidney problems, severe allergic reactions, low magnesium or vitamin B12 levels (especially with long-term use), bone fractures, skin reactions, lupus, and severe gut infections[2][3][4][5][6].
Precautions: Inform your healthcare provider if you experience severe diarrhea, allergic reactions, skin rashes, muscle spasms, irregular heart rate, or symptoms of liver or kidney problems[3][4][5][6]. Use as directed and do not double up doses if a dose is missed[3].
References
- [1] Nexium (Esomeprazole): Uses, side effects, and cautions – Medical News Today
- [2] Common Nexium Side Effects to Know – GoodRx
- [3] Nexium: Uses, Dosage, Side Effects, Warnings – Drugs.com
- [4] Side effects of esomeprazole – NHS
- [5] Esomeprazole (oral route) – Mayo Clinic
- [6] Esomeprazole (Nexium): Uses, Side Effects, Interactions – WebMD
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