Doltrex 50 mg, which contains tramadol hydrochloride, is used for the management of moderate to moderately severe pain, including pain after surgery or pain severe enough to require an opioid analgesic[1][3][6].
The typical uses and key details include:
- Indication: Management of moderate to moderately severe pain[1][3].
- Dosing (Adults and children over 12 years):
- For moderate pain: Initial dose is 50 mg (one tablet), followed by 50 mg or 100 mg every 4-6 hours as needed[2][3][6].
- For severe pain: Initial dose is 100 mg, then 50 mg or 100 mg every 4-6 hours as needed[2][3][6].
- The tablet should be swallowed whole, not divided or chewed, and taken with or without food[2][3].
- The maximum dose should not exceed 400 mg per day[2][3][6][8].
- Duration: Doltrex 50 should not be used longer than necessary; long-term use requires regular medical review due to risk of dependence and side effects[2][3].
- Special precautions:
- Not intended for children below 12 years[2][3].
- Dose adjustment or increased dosing intervals are recommended for elderly patients over 75 years, and for those with liver or kidney impairment[2][3].
- Contraindicated in severe kidney or liver impairment[2][3].
- Should not be used in acute poisoning with alcohol, sleeping pills, other pain relievers, or psychotropic drugs[1].
- Not for use as a substitute in drug withdrawal or by patients with epilepsy[1].
- Serious side effects and increased risk in ultra-rapid metabolisers, those with history of epilepsy or seizures, and risk of hyponatremia have been described[1].
References
- [1] DOLTREX 50 MG film-coated tablet Tramadol hydrochloride 50 mg
- [2] DOLTREX 50 MG Film-coated tablet – PI and PIL Repository
- [3] DOLTREX Film-coated tablet Usage – MPI, Generic – RxReasoner
- [6] Tramadol: Side Effects, Dosage, Uses, and More – Healthline
- [8] Tramadol: Pain Relief Uses, Side Effects, Dosage, Addiction …
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