Menograine does not appear in the medical literature or authoritative sources as an approved or recognized medication for any condition, including migraine. It’s possible there is some confusion with similar-sounding medications or trade names, but based on available evidence, there is no official drug called “menograine” in established pharmacotherapy for headaches or migraines[4][8].
For migraine treatment, a variety of evidence-based medications are commonly used, many with strong data supporting their efficacy. These include:
- Acetaminophen and oral NSAIDs (aspirin, diclofenac, ibuprofen, naproxen) as first-line options[1].
- Triptans (such as sumatriptan, zolmitriptan, rizatriptan), considered the drug of choice for moderate to severe migraine in most patients without vascular disease[1][3][5].
- Antiemetics (such as metoclopramide, promethazine, prochlorperazine), which help with both headache pain and associated nausea[1][5].
- Preventive therapies for frequent or severe migraines may include beta-blockers (propranolol, timolol), antiseizure drugs (topiramate, valproate), or newer CGRP antagonists (such as erenumab, fremanezumab, atogepant, galcanezumab)[2][3][6][7].
The medication menogaril is actually an anthracycline analog developed as a chemotherapy agent for cancer. It has no recognized use in migraine prevention or treatment, was investigated for its anticancer activities, and was not pursued further due to moderate efficacy with notable toxicity in oncology trials[4][8].
References
- [1] Acute Migraine Headache: Treatment Strategies
- [2] Preventive Migraine Treatment | Emgality® (galcanezumab-gnlm)
- [3] Drugs for Migraine
- [4] Menogaril in the treatment of malignant mesothelioma: a phase II study
- [5] Which migraine medications are most helpful?
- [6] QULIPTA® (atogepant) for Migraine Prevention
- [7] Migraine Treatments, Preventative Meds & Abortive Drugs
- [8] Menogaril – Wikipedia
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