Section index
Safety
Most medicine works as expected. When it does not, the questions are urgent and specific: is this reaction normal, did I take too much, should I stop, and do I need a doctor now or can it wait? This section deals with those questions.

If you are worried about symptoms right now and they involve breathing, swelling of the face or throat, chest pain, confusion, uncontrolled bleeding or a suspected overdose, treat it as an emergency. Call 10177 from a landline or 112 from a mobile phone, or contact the Poisons Information Helpline on 0861 555 777 for suspected poisoning or overdose.
What this section covers
Safety pages fall into four broad groups. There are side effect pages, which explain what is common and expected against what is a warning sign. There are allergy and reaction pages, covering how to recognise a genuine allergic reaction and what to do about it. There are dose pages, dealing with missed doses, accidental double doses and overdose concerns. And there are stopping pages, about whether a medicine can be discontinued and what happens if it is stopped suddenly.
Running through all of them is the same distinction: effects that are unpleasant but expected, and effects that mean you should get help without delay.
How to use this section
Match the page to the medicine and to what is actually happening. If you have a rash after antibiotics, the antibiotic reaction pages will be more useful than a general side effect page. If your concern is a dose you missed, read the dose pages rather than the side effect ones.
Note the ingredient, not just the brand. Allergies in particular follow the ingredient and its family, which is why a reaction to one penicillin type antibiotic matters for others in the same group.
These pages describe general patterns. They cannot judge how serious your symptoms are. When something feels wrong, err towards asking rather than reading.
Where to start
- Reactions to antibiotics. Antibiotics Side Effects, Amoxicillin Allergy Symptoms and Penicillin Allergy Symptoms cover the reactions readers ask about most, including how to tell a side effect from an allergy.
- Allergy medicine safety. Antihistamine Safety covers drowsiness, driving, children and older adults.
- Wounds and infection. Infected Cut Symptoms, Signs of Infected Wound and When to See a Doctor for a Wound set out what to watch for, and Who Should Not Use Betadine covers a common antiseptic’s warnings.
- Chronic medicine. Can I Stop Blood Pressure Tablets and Can I Stop Chronic Medication address one of the riskiest decisions people make on their own.
Warning signs that need help now
Some symptoms should never be researched instead of acted on. Get emergency help for swelling of the face, lips, tongue or throat, difficulty breathing or swallowing, a widespread rash with blistering or peeling skin, chest pain, fainting or severe dizziness, confusion or unusual drowsiness, seizures, uncontrolled bleeding, or vomiting blood.
Contact a doctor the same day for a spreading rash without breathing problems, a wound that becomes hot, swollen and increasingly red, fever that starts after a new medicine, yellowing of the eyes or skin, dark urine, severe or persistent vomiting or diarrhoea, or side effects that stop you managing normally.
For a suspected overdose, act immediately even if the person seems fine. Some overdoses, paracetamol in particular, cause serious harm long before symptoms appear. Take the medicine packaging with you.
Finding the right page for your question
If your concern is a combination rather than a single medicine, Interactions is the better section. For information about a specific product, see Medicine, and for the substance behind it, Active Ingredients. If your question is about whether a medicine needs a prescription, see Medicine Schedules.
Common questions
What can I find in the Safety section?
Pages on side effects, allergic reactions, missed and double doses, overdose concerns, warnings about who should avoid a medicine, and when to stop or continue treatment.
How do I choose the right safety page?
Choose by what is happening now. Match the medicine or ingredient to the type of problem, whether that is a reaction, a dose question or a decision about stopping.
Should I ask a pharmacist or doctor?
Yes, whenever symptoms are severe, unexpected, worsening, or affecting someone vulnerable such as a child, an older adult, or someone who is pregnant or breastfeeding. Pharmacists can advise immediately and without an appointment.
Are these pages a substitute for the leaflet?
No. The leaflet lists the approved side effects and warnings for your exact product. Read it, and use these pages to understand what it means in practice.
Should I stop a medicine if I get a side effect?
Not automatically. Some side effects settle within days, and stopping certain medicines suddenly, especially chronic ones, causes its own problems. The exception is a suspected allergic reaction, where you should stop and get help straight away.
All Safety pages
Every page in the Safety section is listed below, in alphabetical order.
A
- Accidental Double Dose Medicine
- Amoxicillin Allergy Symptoms
- Antibiotic Allergy Symptoms
- Antibiotic Rash What to Do
- Antibiotics and Diarrhoea
- Antibiotics During Pregnancy
- Antibiotics Side Effects
- Antidepressant Side Effects
- Antihistamine Safety
- Antihistamines During Pregnancy
B
C
- Can Children Take Adult Medicine
- Can Children Take Allergex
- Can Children Take Ibuprofen
- Can I Stop Amitriptyline Suddenly
- Can I Stop Blood Pressure Tablets
- Can I Stop Chronic Medication
- Can I Stop Taking Statins
- Can I Take Ibuprofen On an Empty Stomach
- Can I Take Painkillers While Pregnant
- Can You Drive After Taking Antihistamines
- Can You Take Antihistamines While Pregnant
- Can You Take Laxatives Every Day
- Child Took Too Much Medicine
- Children and Medicine Safety
- Chronic Medicine Safety Guide
- Ciprofloxacin Tendon Pain
- Cold Medicine Overdose
- Cold Medicine Safety Guide
- Cold Medicine with High Blood Pressure
- Cough Medicine Under 2 South Africa
D
E
F
I
M
- Medicine Allergy Symptoms
- Medicine Dosage for Children
- Medicine During Pregnancy South Africa
- Medicine Rash What to Do
- Medicine Safety for Older Adults
- Medicine Safety South Africa
- Medicine While Breastfeeding
N
P
- Pain Medicine for Children
- Painkiller Safety
- Painkillers During Pregnancy South Africa
- Painkillers While Breastfeeding
- Painkillers with High Blood Pressure
- Paracetamol Overdose Symptoms
- Penicillin Allergy Symptoms
- Purbac Allergy Rash
- Pus From Wound
R
S
- Safe Painkillers During Pregnancy South Africa
- Serious Medicine Side Effects
- Should I Double My Next Dose
- Signs of Infected Wound
- Skin Infection Symptoms
- Statin Muscle Pain
- Steroid Cream Side Effects Skin Thinning
T
- Too Much Ibuprofen Symptoms
- Too Much Panado
- Too Much Paracetamol
- Took Extra Antibiotic Dose
- Took Too Much Medicine What to Do
V
W
- What Happens If You Stop Metformin
- What Happens If You Take Too Much Panado
- When Not to Take Imodium
- When to See a Doctor for a Burn
- When to See a Doctor for Allergies
- When to See a Doctor for Fever
- When to See a Doctor for Severe Headache
- When to See a Doctor for Toothache
- When to See Doctor for Skin Rash
- When to See Doctor for Wound
- When to Seek Help for Medicine Side Effects
- Who Should Not Use Betadine
- Wound Red Swollen Painful
Information only and not a substitute for medical advice. Check the medicine leaflet and ask a pharmacist, doctor or qualified healthcare professional for guidance about your own situation. In an emergency, seek immediate medical help.
Safety and interaction guides
90 pages in this section.
Independent, evidence-based, not a pharmacy
Uses.co.za provides independent medicine information for South Africa. We do not sell medicines and we are not a pharmacy. This page is general information, not personal medical advice.
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