Thiamine 100mg is primarily used to treat or prevent vitamin B1 deficiency, which can occur due to poor dietary intake, chronic alcoholism, certain medical conditions, or after specific surgeries. The usual adult dose for treating mild deficiency is 25mg to 100mg once daily, while for severe deficiency, the dose may be 100mg two or three times a day[7].
Common clinical uses of thiamine 100mg include:
- Treatment of thiamine deficiency, which can lead to conditions such as beriberi and Wernicke-Korsakoff syndrome. Thiamine is especially important for individuals with chronic alcoholism, malabsorption syndromes, or those following bariatric surgery[1][2][6].
- Prevention of Wernicke’s encephalopathy in patients at risk, especially those with a history of heavy alcohol use. Oral or intravenous thiamine is administered, sometimes in higher doses for acute cases[6].
- Support for metabolic processes as thiamine is necessary for converting carbohydrates into energy and maintaining the health of the nervous system, heart, and digestive tract[4][3].
- May be prescribed for children with rare metabolic conditions such as maple syrup urine disease and congenital lactic acidosis, under specialist supervision[4].
Some studies also explore thiamine supplementation to support glucose control in people with type 2 diabetes, usually at doses between 150-300mg per day, though more evidence is required for routine use in this setting[6].
Thiamine is available over the counter in tablets or as part of multivitamin supplements, and higher or injectable doses may be given by healthcare professionals for specific indications[2][5].
It is important to follow healthcare provider instructions on dosage and to note that side effects are uncommon but may include mild stomach upset. Thiamine toxicity from oral supplementation is rare as excess amounts are typically excreted in urine[4].
References
- [1] Thiamine (Vitamin B1) – Uses, Side Effects, and More – WebMD
- [2] Thiamine Uses, Side Effects & Warnings – Drugs.com
- [3] Thiamine Injection: Uses & Side Effects – Cleveland Clinic
- [4] About thiamine – NHS
- [5] Thiamine (oral route, injection route) – Mayo Clinic
- [6] Thiamin – Health Professional Fact Sheet
- [7] How and when to take thiamine – NHS
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