Adco-Napamol is a combination medication that contains naproxen and paracetamol (acetaminophen), used to relieve mild to moderate pain and inflammation associated with conditions such as arthritis, gout, tendonitis, bursitis, menstrual cramps, headache, muscle pain, back pain, and tooth pain[1][5][8]. The combination leverages naproxen’s anti-inflammatory properties and paracetamol’s pain-relieving effects to enhance overall clinical efficacy in conditions marked by pain and inflammation[2].
Naproxen works by blocking substances in the body that cause inflammation and pain, making it especially effective for pain accompanied by swelling or redness, such as in arthritis and acute gout[1][5]. Paracetamol reduces fever and relieves pain but does not reduce inflammation; instead, it works by blocking pain signals in the brain[4][6]. When combined, these two medicines can be safely used together to increase symptom control because they act via different mechanisms and do not significantly interact with each other[2][4][6].
This combination is commonly prescribed for:
- Rheumatoid arthritis and osteoarthritis
- Ankylosing spondylitis
- Acute gout attacks
- Tendinitis and bursitis
- Primary dysmenorrhea (painful periods)
- Headaches, including migraines
- Muscle and back pain
- Toothaches and other mild to moderate pain conditions
Studies have shown that adding paracetamol to naproxen therapy can significantly enhance pain relief in conditions like rheumatoid arthritis, often allowing for lower doses of naproxen and potentially reducing the risk of gastrointestinal side effects associated with higher naproxen doses[2]. For most patients, this combination is safe and effective when taken as directed[4][6]. However, as with any medication, dosages must be determined by a healthcare provider to prevent potential side effects or drug interactions.
References
- [1] Naproxen: Uses, Interactions, Mechanism of Action | DrugBank Online
- [2] Additive effect of combined naproxen and paracetamol in rheumatoid arthritis
- [4] Can I take Naproxen and Paracetamol together?
- [5] Naproxen (Aleve, Naprosyn, others) — Uses, Side Effects, and More | WebMD
- [6] Mixing Naproxen and Acetaminophen
- [8] Naproxen + Paracetamol: View Uses, Side Effects and more — 1mg
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